SCOTUS means the Supreme Court of the United States
SCOTUS is the highest federal court of the United States. It has ultimate (and largely discretionary) appellate jurisdiction over all federal courts and over state court cases involving issues of federal law, plus original jurisdiction over a small range of cases. In the legal system of the United States, the Supreme Court is the final interpreter of federal constitutional law, although it may only act within the context of a case in which it has jurisdiction.
The Court meets in the United States Supreme Court Building in Washington, D.C. The Supreme Court is sometimes referred to as SCOTUS, in analogy to other acronyms such as POTUS.